Mighty Spark Communications
MSC

Selected Work · 2020–2026

Portfolio

Live data visualizations, fluid simulations, full-stack portals, polished marketing sites, and the corporate decks behind them. Everything here was designed and engineered in-house.

Chapter 01 · Interactive UI & Code

The work, working.

Every chart, simulation, and dashboard below is the real thing. Live, interactive, and built by us. Hover, click, and scroll through. This is what we ship for biotech clients.

01.1Data, brought to life

High-end data visualizations

Transform complex assay data into beautiful, interactive charts. We build custom data visualizations that highlight key findings with premium styling, brand color systems, and motion that makes the numbers feel inevitable.

01.1a
·T-Cell activation · dose-response
▣ T-CELL ACTIVATION · CD69 MFI

Synergy in action

Flow Cytometryn=12
CD69 EXPRESSION (MFI)0175350525700ROBUST ACTIVATION0VehicleCONTROL240Agonist AMONOTHERAPY5Agonist BMONOTHERAPY640ComboCOMBINATION✨ SYNERGY · 2.6× MAX
Vehicle
Agonist A
Agonist B
Combo

Source: Jurkat T-Cells, 48 hr

01.1b
·Plasma IL-1β biomarker · cohort variance
▣ PLASMA IL-1β · DAY 28

Variance collapses

HS Arrayn=24
IL-1β (pg/mL)NORMAL RANGE0.00.51.01.50.780.320.18PlaceboLow DoseHigh Dose★ p < 0.001
Placebo
Low Dose
High Dose

High-Sensitivity Multiplex Array

01.1c
·Clinical efficacy + QoL table · animated reveal
▣ LIMB VOLUME REDUCTION · PHASE II

52 weeks. One curve below the other.

N = 124Ongoing

Mean reduction

0%

Responders (≥20%)

0%

Significance

p<0.001

VOLUME CHANGE (%)0-10-20-30-40BASELINEW4W8W12W24W36W52−38%−15%✓ SIGNIFICANT @ W12
Treatment
Standard of Care

95% CI bands · investigational data

01.2Worlds, engineered

WebGL, particles, and scientific simulation

When the brief calls for it, we build Canvas and WebGL backdrops that capture the physical energy of your science: molecular fields, CFD particle simulations of microfluidic devices, fluidic mixers, and convergence diagrams that move in real time.

01.2a
·Particle-driven hero scene
Scientific Background
Immersive Hero Sections

First impressions
engineered to captivate.

We combine high-end 3D renders with custom WebGL particle systems to create dynamic, living backgrounds that immediately establish your scientific credibility.

01.2b
·Convergence model · scroll-linked Venn diagram
DiscoveryClinicalCommercialMSC
Scroll-Linked Animation

The Convergence Model

Scroll the page. The diagram tracks your position, highlights the relevant chapter, and animates particles along the connection that matches, keeping your narrative perfectly synced to the visual.

01

Discovery Phase Integration

Highlighting early-stage pipeline assets, proprietary screening platforms, and the science that started the story.

02

Clinical Translation

Mapping the journey from bench to bedside with clear milestone tracking, biomarker dashboards, and clean trial visuals.

03

Commercial Readiness

Demonstrating market potential, partnerships, and go-to-market. The moment your science meets its audience.

01.2c
·Fluidic mixer · live simulation
▣ MICROFLUIDIC MIXER · LIVE

Nanoparticle formulation dynamics

AQUEOUS INLETLIPID INLETLNP OUTLETLNP
Parameters
50mL/min
3:1
25°C
Reynolds
10,650
Mix Time
4.8ms
Particle
85nm
Live insight·Higher flow rate & lower temp = smaller LNPs. Try adjusting flow rate to see particle size respond.
01.2d
·CFD particle field · drug-delivery dynamics
Live CFD Engine

Computational Fluid Dynamics

Real-time Navier-Stokes approximation visualizing flow around parametric CAD geometries. Used for microfluidic device optimization and nanoparticle formulation scaling.

CAD SourceFR-JET_parametric.step
Velocity Fieldflow_field_v2.vtk
Live ParametersDrag me
2.5m/s
1.00cP
Reynolds No. 2500
Pressure Drop 3.75 kPa
Active Nodes 1600
01.3Pipelines, made visible

Animated clinical pipeline interfaces

Show stakeholders exactly where each program stands. Continuous-flow liquid metaphors, phase-tracking horizontal bars, and interactive program drill-downs, designed to make complex portfolios click instantly.

01.3a
·Continuous-flow pipeline · CellTaxis
▣ CLINICAL PIPELINE · LIVE

Programs in motion

4 programs2 in Phase II

Lymphedema

Phase II — enrolling

ENROLLING
PRE-CLINPHASE IPHASE IIPHASE III

Lipedema

Phase II — dose ranging

ONGOING
PRE-CLINPHASE IPHASE IIPHASE III

Lymphatic Targeting

Preclinical exploration

DISCOVERY
PRE-CLINPHASE IPHASE IIPHASE III

Topical Delivery

Formulation studies

DISCOVERY
PRE-CLINPHASE IPHASE IIPHASE III
Lymphedema
Lipedema
Lymphatic Targeting
Topical Delivery

Continuous-flow visualization

01.3b
·Structured horizontal pipeline · Lytix
Ruxotemitide (LTX-315)- Oncolytic peptide for superficial tumors
Oncolytic Peptide

Registrational Study

Combination with pembrolizumab

Neoadjuvant resectable melanoma patients

PrePh1Ph2Ph3

Ruxotemitide (LTX-315)

Registrational Study - Neoadjuvant Melanoma

Ruxotemitide is an oncolytic peptide that has consistently delivered strong tumor activity, excellent tolerability and clear systemic immune engagement in Phase 2 trials. As a monotherapy, ruxotemitide enables rapid tumor destruction, robust immune cell infiltration and complete regression in injected tumors. Ruxotemitide also delivers abscopal effects in distant metastases, demonstrating clear systemic immune activation.

In combination with immune checkpoint inhibitors, ruxotemitide affords disease control in patients who had previously failed immune checkpoint inhibitor therapy, indicating the impact ruxotemitide can have on the current standard of care for many cancers in the neoadjuvant setting.

Oncolytic Peptide

Monotherapy

Basal cell carcinoma

PrePh1Ph2Ph3
Verrica Pharmaceuticals

Ruxotemitide (LTX-315)

Monotherapy - Basal Cell Carcinoma

Verrica Pharmaceuticals has generated impressive Phase 2 data in basal cell carcinoma with ruxotemitide as a monotherapy. They have reported a 51% complete response rate, and clinical responses in 97% of the patients with significant reduction of tumor size.

Additionally, Verrica has demonstrated that ruxotemitide reprograms the tumor microenvironment, with patient biopsies showing significant increases in CD4+, CD8+ T cells, and B-cells, indicating strong recruitment of effector immune populations into the tumor.

Oncolytic Peptide

NeoLIPA

Investigator-initiated study

Neoadjuvant resectable melanoma patients

PrePh1Ph2Ph3
Currently Recruiting

Ruxotemitide (LTX-315)

NeoLIPA Study

Ruxotemitide is currently being evaluated in an investigator-initiated Phase 2 study 'NeoLIPA' in patients with resectable melanoma prior to surgery. This study is exploring neo-adjuvant ruxotemitide (administered before surgery) in combination with standard of care pembrolizumab (KEYTRUDA®).

The objective of this study is to demonstrate that ruxotemitide improves outcomes in these patients and prevents disease recurrence.

LTX-401- Oncolytic molecule for deep-seated tumors
Oncolytic Molecule

Mono-and combination therapy

Solid tumors (deep seated lesions)

PrePh1Ph2Ph3
Actively Seeking Partnerships

LTX-401

Deep-Seated Solid Tumors

LTX-401 is an oncolytic molecule designed for deep-seated tumors.

LTX-401 expands our oncolytic molecule platform into deep-seated tumors through image-guided intratumoral delivery. This opens access to the liver and other internal tumors where intratumoral treatment has historically not been feasible.

LTX-401 has demonstrated strong proof-of-concept in multiple difficult-to-treat cancer models, including curing animals of liver cancer, and is currently in last-stage pre-clinical development.

01.4Applications that ship

Full-stack portals, dashboards, and commerce

We don't stop at marketing sites. Investor-relations widgets with live tickers, secure client portals for trial management, e-commerce flows tailored for cold-chain biotech logistics. Production software, designed and engineered end-to-end.

01.4a
·Live share-price widget · investor relations
▣ NASDAQ · LIVE

BIOTX Therapeutics Inc

Powered by INFRONT
USD0.00 +0.00%

2026-05-10 · 09:30 ET

Change

+$0.00

High / Low

0.00 / 0.00

Volume

0

Turnover

$0K

8.09.010.011.0JunJulAugSepOctNovDecJanFebMarAprMay$10.85

Ticker

BIOTX

ISIN

US0010405780

Market

NASDAQ

Sector

Biotech

Shares

76.9M

Mkt Cap

$834.4M

01.4b
·Client portal · file vault, tickets, billing
User

Trial Overview

Phase II Study: BX-204 Efficacy

+0%

0

Active Enrolled Patients

0%

Protocol Compliance Rate

0 Action Required

0

Pending SAE Reports

Recent Patient Activity

Patient IDSiteStatusLast Visit
PT-8492Mass GeneralDosedToday, 09:41 AM
PT-8493Mayo ClinicScreeningYesterday
PT-8488Dana-FarberFollow-upOct 24, 2026
01.4c
·Biotech e-commerce · variant + cold-chain logic
▣ PRECISION ORDER · LIVE

Cart / 0 items

Secure Checkout
Order Summary
Subtotal$0.00
Cold Chain $0.00

Temperature-sensitive products ship via specialized cold-chain logistics.

Estimated total$0.00

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